The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 11, 2011
Filed:
Aug. 28, 2007
Yoshihiko Okaichi, Tokushima, JP;
Nobuhito Tada, Tokushima, JP;
Daisuke Nomi, Tokushima, JP;
Nobuhisa Fujita, Tokushima, JP;
Koichi Tsuji, Tokushima, JP;
Taizo Yamaguchi, Tokushima, JP;
Yasuaki Muguruma, Tokushima, JP;
Hisayuki Tsujimori, Saga, JP;
Yoshihiko Okaichi, Tokushima, JP;
Nobuhito Tada, Tokushima, JP;
Daisuke Nomi, Tokushima, JP;
Nobuhisa Fujita, Tokushima, JP;
Koichi Tsuji, Tokushima, JP;
Taizo Yamaguchi, Tokushima, JP;
Yasuaki Muguruma, Tokushima, JP;
Hisayuki Tsujimori, Saga, JP;
Otsuka Pharmaceutical Co., Ltd., Tokyo, JP;
Abstract
The present invention provides a process for producing 1-(3,4-dichlorobenzyl)-5-octylbiguanide or a salt thereof, the process comprising reacting 1-cyano-3-octylguanidine or a salt thereof, with 3,4-dichlorobenzylamine or a salt thereof, in an ester-based organic solvent. According to the present invention, the reaction can be carried out at a low temperature using general-purpose equipment, and 1-(3,4-dichlorobenzyl)-5-octylbiguanide or a salt thereof can be produced in a high yield by a safe and easy process.