The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 11, 2011
Filed:
Mar. 09, 2007
Mahesh Vithalbhai Patel, Aurangabad, IN;
Vijaya Narayan Desai, Aurangabad, IN;
Prasad Keshav Deshpande, Aurangabad, IN;
Ravindra Dattatraya Yeole, Aurangabad, IN;
Rajesh Prabhakar Kale, Amravati, IN;
Mahesh Vithalbhai Patel, Aurangabad, IN;
Vijaya Narayan Desai, Aurangabad, IN;
Prasad Keshav Deshpande, Aurangabad, IN;
Ravindra Dattatraya Yeole, Aurangabad, IN;
Rajesh Prabhakar Kale, Amravati, IN;
Wockhardt Limited, , IN;
Abstract
The instant invention relates to novel prodrugs of optically pure benzoquinolizine-2-carboxylic acid and pharmaceutical compositions that include the prodrugs. In particular, the present invention relates to the sulfonic acid salts of L-alanine and L-valine prodrugs of S-(−)-9-fluoro-6,7-dihydro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acid. The compounds and compositions of the invention can be used to treat bacterial Gram-positive, Gram-negative and anaerobic infections, especially infections caused by resistant Gram-positive organism and Gram-negative organism, mycobacterial infections and emerging nosocomial pathogen infections.