The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 11, 2011
Filed:
Jul. 18, 2006
Gerald Siu, Santa Monica, CA (US);
Wenyan Shen, Thousand Oaks, CA (US);
Steven Kiyoshi Yoshinaga, Thousand Oaks, CA (US);
Haichun Huang, Fremont, CA (US);
Gerald Siu, Santa Monica, CA (US);
Wenyan Shen, Thousand Oaks, CA (US);
Steven Kiyoshi Yoshinaga, Thousand Oaks, CA (US);
Haichun Huang, Fremont, CA (US);
Amgen Inc., Thousand Oaks, CA (US);
Medarex Inc., Princeton, NJ (US);
Abstract
This invention provides antibodies that interact with or bind to human B7 related protein-1 (B7RP1) and antibodies that bind to and neutralize the function of B7RP1 thereby. The invention also provides pharmaceutical compositions of said antibodies and methods for neutralizing B7RP1 function, and particularly for treating immune disorders (e.g., inappropriate immune response) by administering a pharmaceutically effective amount of anti-B7RP1 antibodies. Methods of detecting the amount of B7RP1 in a sample using anti-B7RP1 antibodies are also provided.