The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 11, 2011
Filed:
Dec. 15, 2009
Marcello Allegretti, L'Aquila, IT;
Riccardo Bertini, L'Aquila, IT;
Cinzia Bizzarri, L'Aquila, IT;
Maria Candida Cesta, L'Aquila, IT;
Andrea Aramini, L'Aquila, IT;
Alessio Moriconi, L'Aquila, IT;
Marcello Allegretti, L'Aquila, IT;
Riccardo Bertini, L'Aquila, IT;
Cinzia Bizzarri, L'Aquila, IT;
Maria Candida Cesta, L'Aquila, IT;
Andrea Aramini, L'Aquila, IT;
Alessio Moriconi, L'Aquila, IT;
Dompe' Pha.r.ma S.p.A., L'Aquila, IT;
Abstract
The present invention relates to novel (2R)-2-phenylpropanamides bearing a 4-sulfonylamino substituent on the 4 position of the phenyl group and to pharmaceutical compositions containing them, which are used as inhibitors of the chemotaxis of polymorphonucleate and mononucleate cells, and which are useful in the treatment of various ELR+CXC chemokine-mediated disorders. In particular, the compounds of the invention are useful in the treatment and control of specific CXCR2 dependent pathologies such as BOS, COPD, angiogenesis and melanoma.