The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 11, 2011
Filed:
Feb. 06, 2007
Ellen Baxter, Glenside, PA (US);
Allen B. Reitz, Lansdale, PA (US);
Umar Saibu Mohomed Maharoof, North Wales, PA (US);
Yifang Huang, Lansdale, PA (US);
Christopher John Creighton, San Diego, CA (US);
Charles H. Reynolds, Lansdale, PA (US);
Chi Luo, New Hope, PA (US);
Brett A. Tounge, Blue Bell, PA (US);
Tina Morgan Ross, Royersford, PA (US);
Tianbao LU, Churchville, PA (US);
Ellen Baxter, Glenside, PA (US);
Allen B. Reitz, Lansdale, PA (US);
Umar Saibu Mohomed Maharoof, North Wales, PA (US);
Yifang Huang, Lansdale, PA (US);
Christopher John Creighton, San Diego, CA (US);
Charles H. Reynolds, Lansdale, PA (US);
Chi Luo, New Hope, PA (US);
Brett A. Tounge, Blue Bell, PA (US);
Tina Morgan Ross, Royersford, PA (US);
Tianbao Lu, Churchville, PA (US);
Janssen Pharmaceutica NV, Beerse, BE;
Abstract
The present invention is directed to 2-amino-quinoline derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD) and related disorders. The compounds of the invention are inhibitors of β-secretase, also known as β-site cleaving enzyme and BACE, BACE1, Asp2 and memapsin2.