The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 11, 2011
Filed:
Jul. 11, 2007
Applicants:
Uwe Heinelt, Wiesbaden, DE;
Hans-jochen Lang, Hofheim, DE;
Klaus Wirth, Kriftel, DE;
Thomas Licher, Bad Soden, DE;
Armin Hofmeister, Dexheim, DE;
Inventors:
Uwe Heinelt, Wiesbaden, DE;
Hans-Jochen Lang, Hofheim, DE;
Klaus Wirth, Kriftel, DE;
Thomas Licher, Bad Soden, DE;
Armin Hofmeister, Dexheim, DE;
Assignee:
Sanofi-Aventis, Paris, FR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 217/12 (2006.01); A61K 31/47 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention relates to substituted 4-phenyltetrahydroisoquinolines of formula I wherein R1-R8, N, W, X and Z are defined herein. These compounds and pharmaceutical compositions comprising them are useful in the treatment of respiratory disorders, sleep apnea, kidney disorders, high blood pressure, hypertension, disorders of the central nervous system and the like.