The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 11, 2011

Filed:

Dec. 19, 2006
Applicants:

Hwang-hsing Chen, Fort Worth, TX (US);

Najam A. Sharif, Keller, TX (US);

Mark R. Hellberg, Arlington, TX (US);

Inventors:

Hwang-Hsing Chen, Fort Worth, TX (US);

Najam A. Sharif, Keller, TX (US);

Mark R. Hellberg, Arlington, TX (US);

Assignee:

Alcon Research, Ltd., Fort Worth, TX (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/35 (2006.01); A61K 31/44 (2006.01); A61K 31/551 (2006.01); C07D 213/75 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods for using hydroxyamino- and amino-substituted pyridine analogs are disclosed herein to treat rho kinase-mediated diseases or rho kinase-mediated conditions, including controlling intraocular pressure and treating glaucoma, are disclosed. Ophthalmic pharmaceutical compositions useful in the treatment of eye diseases such as glaucoma, and additionally useful for controlling intraocular pressure, the compositions comprising an effective amount of hydroxyamino- and amino-substituted pyridine analogs, are disclosed herein.


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