The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 11, 2011

Filed:

Jan. 18, 2007
Applicants:

Jean-michel Lerestif, Yvetot, FR;

Jean-pierre Lecouve, Le Havre, FR;

Jean-claude Souvie, Le Havre, FR;

Daniel Brigot, Sainte-Marie-des-Champs, FR;

Stephane Horvath, La-Chapelle-Saint-Mesmin, FR;

Marie-noelle Auguste, Orleans, FR;

Gerard Damien, Meung-sur-Loire, FR;

Inventors:

Jean-Michel Lerestif, Yvetot, FR;

Jean-Pierre Lecouve, Le Havre, FR;

Jean-Claude Souvie, Le Havre, FR;

Daniel Brigot, Sainte-Marie-des-Champs, FR;

Stephane Horvath, La-Chapelle-Saint-Mesmin, FR;

Marie-Noelle Auguste, Orleans, FR;

Gerard Damien, Meung-sur-Loire, FR;

Assignee:

Les Laboratoires Servier, Suresnes Cedex, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 223/16 (2006.01); C07D 405/06 (2006.01); A61K 31/55 (2006.01); A61P 9/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Process for the synthesis of ivabradine of formula (I): addition salts thereof with a pharmaceutically acceptable acid and hydrates thereof. α crystalline form of ivabradine hydrochloride. Medicinal products containing α crystalline form of ivabradine hydrochloride, which are useful as bradycardics.


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