The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 04, 2011

Filed:

Sep. 01, 2005
Applicants:

George W. Muller, Bridgewater, NJ (US);

Roger Chen, Edison, NJ (US);

Manohar Tukaram Saindane, Monmouth Junction, NJ (US);

Chuansheng GE, Belle Mead, NJ (US);

Inventors:

George W. Muller, Bridgewater, NJ (US);

Roger Chen, Edison, NJ (US);

Manohar Tukaram Saindane, Monmouth Junction, NJ (US);

Chuansheng Ge, Belle Mead, NJ (US);

Assignee:

Celgene Corporation, Summit, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention concerns new processes for the preparation of substituted 2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolines which are useful for preventing or treating diseases or conditions related to an abnormally high level or activity of TNFα. The invention provides processes for the commercial production of substituted 2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolines including, but not limited to, the therapeutically active 3-(4-amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione.


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