The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 04, 2011
Filed:
Dec. 26, 2003
Inge Dierynck, Antwerpen, BE;
Jan Ludwig Goeman, Sint-Niklaas, BE;
Koenraad Lodewijk August Van Acker, Temse, BE;
Johan Theo André Van Der Eycken, Ninove, BE;
Inge Dierynck, Antwerpen, BE;
Jan Ludwig Goeman, Sint-Niklaas, BE;
Koenraad Lodewijk August Van Acker, Temse, BE;
Johan Theo André Van Der Eycken, Ninove, BE;
Tibotec BVBA, , BE;
Abstract
This invention relates to hydrolase fluorogenic substrates with improved cell permeability, methods for the preparation thereof, and methods of measuring activities of hydrolases, particularly in cell-based assays. The substrates easily diffuse into the cells, where they are enzymatically processed to yield photostable fluorescent products, and are particularly fitted for visualising enzyme-derived activities in cell-based assays.