The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 04, 2011

Filed:

Nov. 06, 2007
Applicants:

Gary J. Bridger, Bellingham, WA (US);

Ernest J. Mceachern, White Rock, CA;

Renato Skerlj, Vancouver, CA;

Dominique Schols, Herent, BE;

Ian Baird, West Abbotsford, CA;

AL Kaller, Vancouver, CA;

Curtis Harwig, Vancouver, CA;

Yongbao Zhu, Coquitlam, CA;

Gang Chen, Langley, CA;

Krystyna Skupinska, New Westminister, CA;

Inventors:

Gary J. Bridger, Bellingham, WA (US);

Ernest J. McEachern, White Rock, CA;

Renato Skerlj, Vancouver, CA;

Dominique Schols, Herent, BE;

Ian Baird, West Abbotsford, CA;

Al Kaller, Vancouver, CA;

Curtis Harwig, Vancouver, CA;

Yongbao Zhu, Coquitlam, CA;

Gang Chen, Langley, CA;

Krystyna Skupinska, New Westminister, CA;

Assignee:

Genzyme Corporation, Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/02 (2006.01); A61K 31/44 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to compounds that bind to chemokine receptors, and having the formula wherein each A, X, Y, R, Rand Rare substituents. The present invention also relates to methods of using such compounds, such as in treating HIV infection and inflammatory conditions such as rheumatoid arthritis. Furthermore, the present invention relates to methods to elevate progenitor and stem cell counts, as well as methods to elevate white blood cell counts, using such compounds.


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