The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 04, 2011
Filed:
Jul. 12, 2001
Graham P. Allaway, Moreton Merseyside, GB;
Virginia M. Litwin, Fayetteville, NY (US);
Paul J. Maddon, Elmsford, NY (US);
Graham P. Allaway, Moreton Merseyside, GB;
Virginia M. Litwin, Fayetteville, NY (US);
Paul J. Maddon, Elmsford, NY (US);
Progenics Pharmaceuticals Inc., Tarrytown, NY (US);
Abstract
This invention provides agents determined to be capable of inhibiting the fusion of a macrophage-tropic primary isolate of HIV-1 to a CD4cell and agents determined to be capable of inhibiting the fusion of a T cell-tropic isolate of HIV-1 to a CD4cell. This invention also provides methods to identify such agents. This invention further provides methods of inhibiting fusion of a macrophage-tropic primary isolate of HIV-1 with a CD+ cell and methods of inhibiting fusion of a T cell-tropic isolate of HIV-1 with a CD4cell susceptible to infection by a T cell-tropic isolate of HIV-1.