The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 28, 2010
Filed:
Oct. 17, 2005
Milind Moreshwar Gharpure, Maharashtra, IN;
Baburao Manikrao Bhawal, Maharashtra, IN;
Prasad Vasudeo Ranade, Maharashtra, IN;
Rajendra Dagadu Deshmukh, Maharashtra, IN;
Satish Ramanlal Mehta, Maharashtra, IN;
Milind Moreshwar Gharpure, Maharashtra, IN;
Baburao Manikrao Bhawal, Maharashtra, IN;
Prasad Vasudeo Ranade, Maharashtra, IN;
Rajendra Dagadu Deshmukh, Maharashtra, IN;
Satish Ramanlal Mehta, Maharashtra, IN;
Emcure Pharmaceuticals Limited, Maharashtra, IN;
Abstract
The present invention relates to a process for preparation of optically pure (S)-amlodipine-L-hemitartrate DMF solvate comprising the steps of treating (R,S) amlodipine base with L-tartaric acid in the presence of dimethyl formamide and a co-solvent. The invention also relates to a process for converting (R) or (S)-amlopidine-L-hemitartrate DMF solvate into their besylates without isolating free chiral amlopidine base after solution.