The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 28, 2010

Filed:

Jun. 29, 2005
Applicants:

Hiroshi Kawamoto, Tsuchiura, JP;

Satoru Ito, Tsukuba, JP;

Atsushi Satoh, Tsukuba, JP;

Yasushi Nagatomi, Tsukuba, JP;

Yukari Hirata, Tsukuba, JP;

Toshifumi Kimura, Tsukuba, JP;

Gentaroh Suzuki, Tsukuba, JP;

Akio Sato, Ushiku, JP;

Hisashi Ohta, Tsukuba, JP;

Inventors:

Hiroshi Kawamoto, Tsuchiura, JP;

Satoru Ito, Tsukuba, JP;

Atsushi Satoh, Tsukuba, JP;

Yasushi Nagatomi, Tsukuba, JP;

Yukari Hirata, Tsukuba, JP;

Toshifumi Kimura, Tsukuba, JP;

Gentaroh Suzuki, Tsukuba, JP;

Akio Sato, Ushiku, JP;

Hisashi Ohta, Tsukuba, JP;

Assignee:

Banyu Pharmaceutical Co., Ltd., Kudankita, Chiyoda-Ku, Tokyo, JP;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 401/00 (2006.01); A61K 31/44 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to a compound represented by the formula (I): or a pharmaceutically acceptable salt thereof, wherein: Ris a linear or branched alkoxy group, a cycloalkoxy group, a linear or branched lower alkyl group, etc.; Ris halogen atom, a lower alkyl group, etc.; Qis carbon atom or nitrogen atom; Qis carbon atom which may be substituted with oxo group; the formula (III):  (II)is a single bond or a double bond; A is a group selected from the group consisting of the substitutent group α; and Ris hydrogen atom, a lower alkyl group, cyano group, an alkoxy group or a trialkylsilyl group; having an mGluR1 inhibiting action and being useful as treatment and/or prevention of convulsion, acute pain, cerebral disturbance such as cerebral infarction or transient cerebral ischemia onset, anxiety, chemical dependency or Parkinson's disease.


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