The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 28, 2010
Filed:
Jan. 26, 2009
Applicants:
Bruce Thomas Dembofsky, Wilmington, DE (US);
Robert Jacobs, Wake Forest, NC (US);
Cyrus Ohnmacht, Wilmington, DE (US);
Inventors:
Bruce Thomas Dembofsky, Wilmington, DE (US);
Robert Jacobs, Wake Forest, NC (US);
Cyrus Ohnmacht, Wilmington, DE (US);
Assignee:
AstraZeneca AB, Sodertalje, SE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 223/16 (2006.01);
U.S. Cl.
CPC ...
Abstract
Compounds having the formula (I) pharmaceutical compositions containing them and their methods of use for the treatment of neurological disorders related to amyloid β protein production and neurological disorders such as Alzheimer's disease. These compounds inhibit γ secretase and thereby inhibit the production of amyloid β protein, thereby acting to prevent the formation of neurological deposits of amyloid protein.