The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 28, 2010

Filed:

Jul. 26, 2002
Applicants:

Katherine D Collier, Redwood City, CA (US);

Edwin Lee, San Francisco, CA (US);

Nicholas Leiva, San Francisco, CA (US);

Thomas B Morrison, Winchester, MA (US);

Volker Schellenberger, Palo Alto, CA (US);

Olga V Selifonova, Plymouth, MN (US);

Adam C Kean, Palo Alto, CA (US);

Inventors:

Katherine D Collier, Redwood City, CA (US);

Edwin Lee, San Francisco, CA (US);

Nicholas Leiva, San Francisco, CA (US);

Thomas B Morrison, Winchester, MA (US);

Volker Schellenberger, Palo Alto, CA (US);

Olga V Selifonova, Plymouth, MN (US);

Adam C Kean, Palo Alto, CA (US);

Assignee:

Genencor International, Inc., Palo Alto, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); C07H 21/04 (2006.01); A61K 39/38 (2006.01); A61K 39/07 (2006.01);
U.S. Cl.
CPC ...
Abstract

An evolvable production strain ofexhibiting continuous or high level expression during protein evolution is described. An evolvedpstS promoter facilitates screening and production of secreted proteins.


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