The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 28, 2010
Filed:
Mar. 29, 2005
Jonathan Henry Ellis, Stevenage, GB;
Alexandre Eon-duval, Fenil-sur-Corsier, CH;
Volker Germaschewski, Stevenage, GB;
Christopher Plumpton, Stevenage, GB;
Nicholas Timothy Rapson, Cambridge, GB;
Michael Robert West, Stevenage, GB;
Jonathan Henry Ellis, Stevenage, GB;
Alexandre Eon-Duval, Fenil-sur-Corsier, CH;
Volker Germaschewski, Stevenage, GB;
Christopher Plumpton, Stevenage, GB;
Nicholas Timothy Rapson, Cambridge, GB;
Michael Robert West, Stevenage, GB;
Glaxo Group Limited, , GB;
Abstract
The present invention concerns immunoglobulins, such as antibodies, which specifically bind Oncostatin M (OSM), particularly human OSM (hOSM) and modulate the interaction between OSM and gp130. In typical embodiments, OSM is glycosylated. The invention also concerns antibodies that modulate the interaction between both Site II and Site III of OSM and their respective interacting partners. Further disclosed are pharmaceutical compositions, screening and medical treatment methods.