The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 28, 2010
Filed:
Sep. 29, 2006
Michael Colin Cramp, Essex, GB;
Rosa Arienzo, Essex, GB;
George Hynd, Essex, GB;
Peter Crackett, Hertfordshire, GB;
Yann Griffon, Essex, GB;
Trevor Keith Harrison, Essex, GB;
Nicholas Charles Ray, Essex, GB;
Harry Finch, Essex, GB;
John Gary Montana, Essex, GB;
Michael Colin Cramp, Essex, GB;
Rosa Arienzo, Essex, GB;
George Hynd, Essex, GB;
Peter Crackett, Hertfordshire, GB;
Yann Griffon, Essex, GB;
Trevor Keith Harrison, Essex, GB;
Nicholas Charles Ray, Essex, GB;
Harry Finch, Essex, GB;
John Gary Montana, Essex, GB;
Pulmagen Therapeutics (Asthma) Limited, Slough, GB;
Abstract
Compounds of formula [1] are CRTH2 antagonists, useful in the treatment of conditions having an inflammatory components; in which: R-Rare various substituents; A is —CHR—, —C(O)—, —S(O)n—, —O—, or —NR— wherein n is an integer from 0-1 and Ris selected from various substituents; B is a direct bond or a divalent radical; Rand Rare selected from cvarious substituents; X is a carboxylic acid, tetrazole, 3-hydroxyisoxazole, hydroxamic acid, phosphinate, phosphonate, phosphonamide, sulfonic acid group, or a group of formula C═(O)NHSORor SONHC(═O)R; and Y is aryl, heteroaryl, aryl-fused-heterocycloalkyl, heteroaryl-fused-cycloalkyl, heteroaryl-fused-heterocycloalkyl or aryl-fused-cycloalkyl group.