The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 28, 2010

Filed:

Apr. 05, 2007
Applicants:

John J. Baldwin, Gwynedd Valley, PA (US);

David A. Claremon, Maple Glen, PA (US);

Colin M. Tice, Ambler, PA (US);

Salvacion Cacatian, Blue Bell, PA (US);

Lawrence W. Dillard, Yardley, PA (US);

Alexey V. Ishchenko, Somerville, MA (US);

Jing Yuan, Lansdale, PA (US);

Zhenrong Xu, Horsham, PA (US);

Gerard Mcgeehan, Garnet Valley, PA (US);

Wei Zhao, Eagleville, PA (US);

Robert D. Simpson, Wilmington, DE (US);

Suresh B. Singh, Kendall Park, NJ (US);

Inventors:

John J. Baldwin, Gwynedd Valley, PA (US);

David A. Claremon, Maple Glen, PA (US);

Colin M. Tice, Ambler, PA (US);

Salvacion Cacatian, Blue Bell, PA (US);

Lawrence W. Dillard, Yardley, PA (US);

Alexey V. Ishchenko, Somerville, MA (US);

Jing Yuan, Lansdale, PA (US);

Zhenrong Xu, Horsham, PA (US);

Gerard McGeehan, Garnet Valley, PA (US);

Wei Zhao, Eagleville, PA (US);

Robert D. Simpson, Wilmington, DE (US);

Suresh B. Singh, Kendall Park, NJ (US);

Assignee:

Vitae Pharmaceuticals, Inc., Fort Washington, PA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/5355 (2006.01); A61K 31/4402 (2006.01); A61K 31/4525 (2006.01); A61K 31/445 (2006.01); C07D 411/12 (2006.01); C07D 213/30 (2006.01); C07D 403/12 (2006.01); C07D 405/12 (2006.01); C07D 401/12 (2006.01); C07D 211/22 (2006.01);
U.S. Cl.
CPC ...
Abstract

Described are compounds which are orally active and bind to renin to inhibit its activity. They are useful in the treatment or amelioration of diseases associated with renin activity. Also described are methods of use of these compounds for treating or ameliorating a renin mediated disorder in a subject.


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