The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 28, 2010

Filed:

Nov. 29, 2005
Applicants:

Takeshi Ohshima, Kounosu, JP;

Hiroyoshi Hidaka, Nagoya, JP;

Masami Shiratsuchi, Musashimurayama, JP;

Kazuhiro Onogi, Iruma, JP;

Toshiaki Oda, Higashimurayama, JP;

Inventors:

Takeshi Ohshima, Kounosu, JP;

Hiroyoshi Hidaka, Nagoya, JP;

Masami Shiratsuchi, Musashimurayama, JP;

Kazuhiro Onogi, Iruma, JP;

Toshiaki Oda, Higashimurayama, JP;

Assignees:

Kowa Co., Ltd., Nagoya-shi, JP;

D. Western Therapeutics Institute, Inc., Nagoya-shi, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61P 9/10 (2006.01); A61K 31/551 (2006.01); C07D 401/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to (S)-(−)-1-(4-fluoroisoquinolin-5-yl)sulfonyl-2-methyl-1,4-homopiperazine hydrochloride dihydrate, to a method producing the dihydrate, and to a drug composition containing the dihydrate. The compound of the present invention has less hygroscopicity as compared with (S)-(−)-1-(4-fluoroisoquinolin-5-yl)sulfonyl-2-methyl-1,4-homopiperazine hydrochloride anhydrous crystals and thus, exhibits excellent chemical stability.


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