The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 28, 2010
Filed:
Dec. 17, 2008
Tomohisa Ninomiya, Kawasaki, JP;
Takashi Shishikura, Yokohama, JP;
Mitsuhiro Uchida, Kawasaki, JP;
Sho Takahata, Yokohama, JP;
Yukari Hoshina, Ebina, JP;
Ken-ichi Kawano, Hamamatsu, JP;
Tomohisa Ninomiya, Kawasaki, JP;
Takashi Shishikura, Yokohama, JP;
Mitsuhiro Uchida, Kawasaki, JP;
Sho Takahata, Yokohama, JP;
Yukari Hoshina, Ebina, JP;
Ken-ichi Kawano, Hamamatsu, JP;
Meiji Seika Kaisha, Ltd., Tokyo, JP;
Abstract
The present invention relates to a method for maintaining the remission of or treating inflammatory bowel diseases, which comprises administering a maintenance therapeutically effective amount or a therapeutically effective amount of 7,8-dimethoxy-4(5H),10-dioxo-1H-1,2,3-triazolo[4,5-c][1]benzoazepine, a prodrug thereof, or a pharmaceutically acceptable salt thereof to a mammal, wherein the prodrug is 2-(1-isopropoxycarbonyloxy-2-methylpropyl)-7,8-dimethoxy-4(5H),10-dioxo-2H-1,2,3-triazolo[4,5-c][1]benzoazepine. The method according to the present invention is effective in the maintenance therapy and therapy of the inflammatory bowel diseases and has few side effects. Particularly, the method according to the present invention may exhibit strong maintenance therapeutic and therapeutic effects, even on severe cases having resistance to the conventional therapeutics.