The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 28, 2010
Filed:
Aug. 28, 2007
Victor P. Chu, Hockessin, DE (US);
Zhu Teng, Boothwyn, PA (US);
Steve P. A. Goss, Wilmington, DE (US);
Ronald A. Edwards, Bear, DE (US);
Kelle M. Garvey, Wilmington, DE (US);
Timothy J. Gorzynski, Newark, DE (US);
William D. Bedzyk, Odessa, DE (US);
Victor P. Chu, Hockessin, DE (US);
Zhu Teng, Boothwyn, PA (US);
Steve P. A. Goss, Wilmington, DE (US);
Ronald A. Edwards, Bear, DE (US);
Kelle M. Garvey, Wilmington, DE (US);
Timothy J. Gorzynski, Newark, DE (US);
William D. Bedzyk, Odessa, DE (US);
Siemens Healthcare Diagnostics Inc., Deerfield, IL (US);
Abstract
The present invention relates to immobilized procainamide analogs, as well as to a method of making immobilized procainamide analogs. These immobilized analogs are prepared by activating the carboxyl group on a substituted p-benzoic acid derivative toward nucleophilic attack; reacting the activated benzoic acid derivative with a polyamine to produce the benzoic acid derivative of Formula 3: and binding the benzoic acid derivative of Formula 3 to a latex polymer having functional groups that react with aliphatic amino groups. A method of conducting an immunoassay using the immobilized procainamide analog Formula 3 is described, comprising the steps of preparing a solution comprising said immobilized procainamide analog; adding a sample suspected of containing procainamide to said solution; adding an anti-procainamide antibody to said solution and observing the rate of increase in solution turbidity following antibody addition.