The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 28, 2010
Filed:
Mar. 03, 2008
Achim Müller, Grossostheim, DE;
Monika Knuth, Aschaffenburg, DE;
Katharina Schmid, Aschaffenburg, DE;
Ralf Pasternack, Griesheim, DE;
Jens Zotzel, Darmstadt, DE;
Kai Oertel, Mainz, DE;
Christine Reiff, Geb. Schmitt, Lörrach, DE;
Hans-lothar Fuchsbauer, Mühltal, DE;
Achim Müller, Grossostheim, DE;
Monika Knuth, Aschaffenburg, DE;
Katharina Schmid, Aschaffenburg, DE;
Ralf Pasternack, Griesheim, DE;
Jens Zotzel, Darmstadt, DE;
Kai Oertel, Mainz, DE;
Christine Reiff, geb. Schmitt, Lörrach, DE;
Hans-Lothar Fuchsbauer, Mühltal, DE;
Novartis AG, Basel, CH;
Abstract
The invention relates to a process for the manufacture of a composite materials comprising the steps of (a) providing a hydrophobic organic bulk material, and (b) applying a hydrophilic surface coating on the hydrophobic organic bulk material by first non-covalently attaching to the surface of the bulk material a water-soluble peptide comprising a hydrophobic moiety; and then chemically or enzymatically crosslinking the water-soluble peptide. The composite materials manufactured according to the process of the invention have desirable characteristics regarding adherence to the substrate, durability, hydrophilicity, wettability, biocompatibility and permeability and are thus particularly useful as ophthalmic devices.