The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 28, 2010

Filed:

Jul. 25, 2007
Applicants:

Ronald P. Taylor, Charlottesville, VA (US);

Margaret A. Lindorfer, Charlottesville, VA (US);

Michael D. Solga, Charlottesville, VA (US);

Adam Kennedy, Charlottesville, VA (US);

Inventors:

Ronald P. Taylor, Charlottesville, VA (US);

Margaret A. Lindorfer, Charlottesville, VA (US);

Michael D. Solga, Charlottesville, VA (US);

Adam Kennedy, Charlottesville, VA (US);

Assignee:

University of Virginia Patent Foundation, Charlottesville, VA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 35/16 (2006.01); C12P 21/08 (2006.01); C07K 16/28 (2006.01); C07K 19/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to a composition and method for enhancing the complement-mediated cytotoxicity of therapeutic antibodies for their target cells (i.e. those cells displaying the target epitope). More particularly the present invention enhances the efficacy of such therapies by providing a supplemental source of complement.


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