The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 21, 2010

Filed:

Jun. 13, 2007
Applicants:

James Arnold, Wilmington, DE (US);

Phil Edwards, Wilmington, DE (US);

Mark Sylvester, Wilmington, DE (US);

Stefan Berg, Södertälje, SE;

Jörg Holenz, Södertälje, SE;

Annika Kers, Södertälje, SE;

Karin Kolmodin, Södertälje, SE;

Laszlo Rakos, Södertälje, SE;

Liselotte Öhberg, Södertälje, SE;

Rotticci Didier, Södertälje, SE;

Gianni Chessari, Cambridge, GB;

Miles Congreve, Cambridge, GB;

Christopher Murray, Cambridge, GB;

Sahil Patel, Cambridge, GB;

Inventors:

James Arnold, Wilmington, DE (US);

Phil Edwards, Wilmington, DE (US);

Mark Sylvester, Wilmington, DE (US);

Stefan Berg, Södertälje, SE;

Jörg Holenz, Södertälje, SE;

Annika Kers, Södertälje, SE;

Karin Kolmodin, Södertälje, SE;

Laszlo Rakos, Södertälje, SE;

Liselotte Öhberg, Södertälje, SE;

Rotticci Didier, Södertälje, SE;

Gianni Chessari, Cambridge, GB;

Miles Congreve, Cambridge, GB;

Christopher Murray, Cambridge, GB;

Sahil Patel, Cambridge, GB;

Assignees:

AstraZeneca AB, Sodertalje, SE;

Astex Therapeutics Ltd., Cambridge, GB;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/506 (2006.01); C07D 403/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention relates to novel compounds having the structural formula I below: and to their pharmaceutically acceptable salt, compositions and methods of use. These novel compounds provide a treatment or prophylaxis of cognitive impairment, Alzheimer Disease, neurodegeneration and dementia.


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