The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 21, 2010

Filed:

May. 03, 2004
Applicants:

Matthias Schwarz, Geneva, CH;

Pascale Gaillard, Collonges sous Saleve, FR;

Jean-pierre Gotteland, Beaumont, FR;

Russell J. Thomas, Siena, IT;

Patrick Page, Saint-Julien-en-Genevois, FR;

Inventors:

Matthias Schwarz, Geneva, CH;

Pascale Gaillard, Collonges sous Saleve, FR;

Jean-Pierre Gotteland, Beaumont, FR;

Russell J. Thomas, Siena, IT;

Patrick Page, Saint-Julien-en-Genevois, FR;

Assignee:

Merck Serono SA, Coinsins, CH;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 43/54 (2006.01); C07D 239/42 (2006.01); C07D 401/04 (2006.01); C07D 239/02 (2006.01); C07D 401/00 (2006.01); C07D 403/00 (2006.01); C07D 405/00 (2006.01); C07D 409/00 (2006.01); C07D 411/00 (2006.01); C07D 413/00 (2006.01); C07D 417/00 (2006.01); C07D 419/00 (2006.01); A61K 31/505 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is related to pyridinyl acetonitriles as well as to pharmaceutical formulations containing such pyridinyl acetonitriles. Said pyridinyl acetonitriles are modulators of the protein kinase signalling pathways, particularly the one involving Glycogen Kinase Synthase 3 or JNK. The present invention is furthermore related to methods of preparing pyridinyl acetonitriles. X is a substituted or unsubstituted pyridinyl. G is an unsubstituted or substituted pyrimidinyl or triazinyl.


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