The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 21, 2010
Filed:
Jul. 24, 2006
Ashis K. Saha, Stow, MA (US);
Nili Schutz, Tel-Aviv, IL;
Xiang Yu, Acton, MA (US);
Dilara Mccauley, Cambridge, MA (US);
Mercedes Lobera, Concord, MA (US);
Yael Marantz, Kadima, IL;
Jian Lin, Walpole, MA (US);
Srinivasa R. Cheruku, Lexington, MA (US);
Pini Orbach, Needham, MA (US);
Anurag Sharadendu, Bedford, MA (US);
Robert Christian Penland, Watertown, MA (US);
Kimberley Gannon, Watertown, MA (US);
Sharon Shacham, Newton, MA (US);
Silvia Noiman, Herzliyya, IL;
Oren Becker, Mevaseret Zion, IL;
Ashis K. Saha, Stow, MA (US);
Nili Schutz, Tel-Aviv, IL;
Xiang Yu, Acton, MA (US);
Dilara McCauley, Cambridge, MA (US);
Mercedes Lobera, Concord, MA (US);
Yael Marantz, Kadima, IL;
Jian Lin, Walpole, MA (US);
Srinivasa R. Cheruku, Lexington, MA (US);
Pini Orbach, Needham, MA (US);
Anurag Sharadendu, Bedford, MA (US);
Robert Christian Penland, Watertown, MA (US);
Kimberley Gannon, Watertown, MA (US);
Sharon Shacham, Newton, MA (US);
Silvia Noiman, Herzliyya, IL;
Oren Becker, Mevaseret Zion, IL;
EPIX Pharmaceuticals, Inc., Lexington, MA (US);
Abstract
The present invention relates to compounds of the general formula (I) that have activity as S1P receptor modulating agents and the use of such compounds to treat diseases associated with inappropriate S1P receptor activity. The compounds may be used as immunomodulators, e.g., for treating or preventing diseases such as autoimmune and related immune disorders including systemic lupus erythematosus, inflammatory bowel diseases such as Crohn's disease and ulcerative colitis, type I diabetes, uveitis, psoriasis, myasthenia gravis, rheumatoid arthritis, non-glomerular nephrosis, hepatitis, Behçet's disease, glomerulonephritis, chronic thrombocytopenic purpura, hemolytic anemia, hepatitis and Wegner's granuloma; and for treating other conditions.