The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 21, 2010
Filed:
Jan. 23, 2008
Applicants:
Gary W. Ashley, Alameda, CA (US);
Hugo Menzella, Castro Valley, CA (US);
Janice Lau Wee, San Mateo, CA (US);
John R. Carney, Foster City, CA (US);
Inventors:
Gary W. Ashley, Alameda, CA (US);
Hugo Menzella, Castro Valley, CA (US);
Janice Lau Wee, San Mateo, CA (US);
John R. Carney, Foster City, CA (US);
Assignee:
Kosan Biosciences, Inc., Princeton, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 225/06 (2006.01); A61K 31/395 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
Macrolactams are made by feeding aromatic amino acids as replacement starter units to a mutant strain of the geldanamycin-producing microorganismvar.NRRL 3602, wherein the gene cluster encoding enzymes for the biosynthesis of the natural starter unit 3-amino-5-hydroxybenzoic acid has been deleted.