The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 14, 2010

Filed:

Nov. 27, 2006
Applicants:

Qingjie Ding, Bridgewater, NJ (US);

Bradford James Graves, Nutley, NJ (US);

Norman Kong, West Caldwell, NJ (US);

Jin-jun Liu, Warren Township, NJ (US);

Allen John Lovey, North Caldwell, NJ (US);

Giacomo Pizzolato, Glen Ridge, NJ (US);

John Lawson Roberts, Budd Lake, NJ (US);

Sung-sau SO, Nutley, NJ (US);

Binh Thanh VU, North Caldwell, NJ (US);

Peter Michael Wovkulich, Nutley, NJ (US);

Inventors:

Qingjie Ding, Bridgewater, NJ (US);

Bradford James Graves, Nutley, NJ (US);

Norman Kong, West Caldwell, NJ (US);

Jin-Jun Liu, Warren Township, NJ (US);

Allen John Lovey, North Caldwell, NJ (US);

Giacomo Pizzolato, Glen Ridge, NJ (US);

John Lawson Roberts, Budd Lake, NJ (US);

Sung-Sau So, Nutley, NJ (US);

Binh Thanh Vu, North Caldwell, NJ (US);

Peter Michael Wovkulich, Nutley, NJ (US);

Assignee:

Hoffmann-La Roche Inc., Nutley, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/02 (2006.01); C07D 233/06 (2006.01); A61K 31/497 (2006.01); A01N 43/50 (2006.01);
U.S. Cl.
CPC ...
Abstract

There is provided a compound of formula I and the pharmaceutically acceptable salts and esters thereofwherein X, X, R, R, R, R, Rand Rare herein described. The compounds exhibit activity as anticancer agents.


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