The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 14, 2010

Filed:

Mar. 28, 2008
Applicants:

Bradley P. Morgan, Moraga, CA (US);

David J. Morgans, Jr., Los Altos, CA (US);

Gustave Bergnes, Pacifica, CA (US);

Alex Muci, San Francisco, CA (US);

Scott Collibee, San Carlos, CA (US);

Pu-ping LU, Foster City, CA (US);

Luke W. Ashcraft, San Francisco, CA (US);

William F. Browne, Iv, Tannersville, NY (US);

Marc Andrew Garard, Oakland, CA (US);

Inventors:

Bradley P. Morgan, Moraga, CA (US);

David J. Morgans, Jr., Los Altos, CA (US);

Gustave Bergnes, Pacifica, CA (US);

Alex Muci, San Francisco, CA (US);

Scott Collibee, San Carlos, CA (US);

Pu-Ping Lu, Foster City, CA (US);

Luke W. Ashcraft, San Francisco, CA (US);

William F. Browne, IV, Tannersville, NY (US);

Marc Andrew Garard, Oakland, CA (US);

Assignee:

Cytokinetics, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/444 (2006.01); C07D 471/02 (2006.01); A61P 21/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Provided are certain chemical entities, and methods of use to modulate skeletal myosin, skeletal actin, skeletal tropomyosin, skeletal troponin C, skeletal troponin I, skeletal troponin T, and skeletal muscle, including fragments and isoforms thereof, as well as the skeletal sarcomere, and methods of use in the treatment of muscle weakness and/or cachexia, as part of a rehabilitation or conditioning exercise regimen, or in the treatment of fraility, post-polio syndrome, obesity, sarcopenia, wasting syndrome, muscle spasm, and other indications.


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