The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 14, 2010
Filed:
Jul. 28, 2006
Linghong Xie, Guilford, CT (US);
Joseph W. Ochterski, Middlefield, CT (US);
Yang Gao, Madison, CT (US);
Bingsong Han, North Haven, CT (US);
Timothy M. Caldwell, Guilford, CT (US);
Yuelian Xu, East Haven, CT (US);
John M. Peterson, Durham, CT (US);
Ping GE, Durham, CT (US);
Robert Ohliger, Deep River, CT (US);
Linghong Xie, Guilford, CT (US);
Joseph W. Ochterski, Middlefield, CT (US);
Yang Gao, Madison, CT (US);
Bingsong Han, North Haven, CT (US);
Timothy M. Caldwell, Guilford, CT (US);
Yuelian Xu, East Haven, CT (US);
John M. Peterson, Durham, CT (US);
Ping Ge, Durham, CT (US);
Robert Ohliger, Deep River, CT (US);
Neurogen Corporation, Branford, CT (US);
Abstract
Dipiperazinyl ketones and related analogues are provided, as are methods for their preparation and use. Such compounds may generally be used to modulate ligand binding to histamine H3 receptors in vivo or in vitro, and are particularly useful in the treatment of a variety of disorders in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and therapeutic methods are provided, as are methods for using such ligands for detecting histamine H3 receptors (e.g., receptor localization studies).