The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 14, 2010

Filed:

Apr. 03, 2003
Applicants:

Ning Wei, Roswell, GA (US);

Yanbin Huang, Roswell, GA (US);

Kaiyuan Yang, Cumming, GA (US);

Inventors:

Ning Wei, Roswell, GA (US);

Yanbin Huang, Roswell, GA (US);

Kaiyuan Yang, Cumming, GA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12M 1/34 (2006.01);
U.S. Cl.
CPC ...
Abstract

A membrane-based assay device for detecting the presence or quantity of an analyte residing in a test sample is provided. The device utilizes conjugated probes that contain a specific binding member for the analyte of interest. The specific binding member preferentially complexes with the analyte within a test sample when contacted therewith. Excess analyte that remains uncomplexed with the specific binding member undergoes non-specific binding, such as to a hydrophobic domain. As a result, the ability of the uncomplexed analyte to compete with the complexed analyte at the detection zone of the device is restricted. Thus, the incidence of 'false negatives' is limited in a simple, efficient, and relatively inexpensive manner.


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