The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 14, 2010
Filed:
Oct. 01, 2003
Sonia E. Létant, Livermore, CA (US);
Anthony W. Van Buuren, Livermore, CA (US);
Louis J. Terminello, Danville, CA (US);
Michael P. Thelen, Danville, CA (US);
Louisa J. Hope-weeks, Brentwood, CA (US);
Bradley R. Hart, Brentwood, CA (US);
Sonia E. Létant, Livermore, CA (US);
Anthony W. van Buuren, Livermore, CA (US);
Louis J. Terminello, Danville, CA (US);
Michael P. Thelen, Danville, CA (US);
Louisa J. Hope-Weeks, Brentwood, CA (US);
Bradley R. Hart, Brentwood, CA (US);
Lawrence Livermore National Security, LLC, Livermore, CA (US);
Abstract
Disclosed are nanometer to micron scale functionalized apertures constructed on a substrate made of glass, carbon, semiconductors or polymeric materials that allow for the real time detection of biological materials or chemical moieties. Many apertures can exist on one substrate allowing for the simultaneous detection of numerous chemical and biological molecules. One embodiment features a macrocyclic ring attached to cross-linkers, wherein the macrocyclic ring has a biological or chemical probe extending through the aperture. Another embodiment achieves functionalization by attaching chemical or biological anchors directly to the walls of the apertures via cross-linkers.