The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 14, 2010
Filed:
Jun. 14, 2005
Applicants:
Lewis Markoff, Bethesda, MD (US);
LI Yu, Gaithersburg, MD (US);
Inventors:
Lewis Markoff, Bethesda, MD (US);
Li Yu, Gaithersburg, MD (US);
Assignee:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/00 (2006.01); C12N 7/04 (2006.01); C12N 15/86 (2006.01); A61K 39/12 (2006.01); A61K 39/295 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention provides West Nile (WN) viruses and chimeric WN viruses having one or more mutations in the 3' terminal stem loop secondary structure (3′SL) that results in decreased neurovirulence, methods of making such WN viruses, and methods for using these WN viruses to prevent or treat WN virus infection.