The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 14, 2010
Filed:
Dec. 22, 2006
Applicants:
Dirk Seegert, Danischenhagen, DE;
Georg H. Waetzig, Kiel, DE;
Inventors:
Dirk Seegert, Danischenhagen, DE;
Georg H. Waetzig, Kiel, DE;
Assignee:
Conaris Research Institute AG, Kiel, DE;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/09 (2006.01); C12N 15/11 (2006.01); C12N 15/12 (2006.01); C12N 15/63 (2006.01); C12N 1/20 (2006.01); C12N 1/15 (2006.01); C12N 5/07 (2006.01); C07K 14/00 (2006.01); C07K 14/435 (2006.01);
U.S. Cl.
CPC ...
Abstract
A polypeptide-dimer built of two identical monomeric fragments comprising the domains 1 to 3 of the extracellular (soluble) part of glycoprotein (gp)130 and a certain polypeptide spacer are described, which are covalently linked with each other and which bear significant advantages concerning their production rate in host cells, their improved purification and their potential to bind to IL-6/soluble IL-6 receptor complexes. Furthermore, a pharmaceutical composition containing said dimeric molecule and various medical uses are described.