The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 14, 2010
Filed:
Aug. 16, 2007
Teresa A. Brentnall, Seattle, WA (US);
RU Chen, Seattle, WA (US);
Katherine L. Pogue-geile, Pittsburgh, PA (US);
David C. Whitcomb, Allison Park, PA (US);
Mary Patricia Bronner, Moreland Hills, OH (US);
Carol A. Otey, Chapel Hill, NC (US);
Teresa A. Brentnall, Seattle, WA (US);
Ru Chen, Seattle, WA (US);
Katherine L. Pogue-Geile, Pittsburgh, PA (US);
David C. Whitcomb, Allison Park, PA (US);
Mary Patricia Bronner, Moreland Hills, OH (US);
Carol A. Otey, Chapel Hill, NC (US);
The University of Washington, Seattle, WA (US);
The University of North Carolina at Chapel Hill, Chapel Hill, NC (US);
The University of Pittsburgh, Pittsburgh, PA (US);
The Cleveland Clinic Foundation, Cleveland, OH (US);
Abstract
The present invention provides methods and compositions involving detecting the presence of and/or assessing the risk of cancer in a subject. These methods include methods of detecting and diagnosing cancer in an individual; methods of identifying individuals at risk of developing a cancer; and methods of staging a cancer. The methods generally involve detecting a palladin gene nucleotide sequence alteration that has been found to be associated with cancer and/or detecting a level of a palladin mRNA and/or protein in a biological sample. The present invention further provides nucleic acid probes, nucleic acid primers, and antibodies, as well as kits comprising one or more of the same, for use in a subject method.