The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 14, 2010

Filed:

Sep. 11, 2007
Applicants:

H. William Bosch, King of Prussia, PA (US);

Eugene R. Cooper, King of Prussia, PA (US);

Simon L. Mcgurk, King of Prussia, PA (US);

Inventors:

H. William Bosch, King of Prussia, PA (US);

Eugene R. Cooper, King of Prussia, PA (US);

Simon L. McGurk, King of Prussia, PA (US);

Assignee:

Elan Pharma International, Ltd., Athlone, County Westmeath, IE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/14 (2006.01);
U.S. Cl.
CPC ...
Abstract

Bioadhesive nanoparticulate compositions, comprising active agent particles and one or more cationic surface stabilizers, are described. The cationic surface stabilizers prevent aggregation of the nanoparticles and increase bioadhesion of the nanoparticles to biological substrates, such as an insect, teeth, bone, nails, chitin, feathers, scales, mucous, skin, hair, plant tissue, etc. The particles may consist of pharmacologically active compounds (e.g., drug compounds for human or veterinary use), agricultural chemicals (pesticides, herbicides, fertilizers, and the like), cosmetic agents, consumer products (coloring agents, flavors, or fragrances), or other materials which function by interacting with biological substrates. In addition, the invention relates to methods of preparing and using such bioadhesive nanoparticulate compositions.


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