The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 07, 2010
Filed:
May. 29, 2003
Applicants:
Dongcheng Dai, Mountain View, CA (US);
John H. Musser, San Carlos, CA (US);
Edwin S. Lennox, Stanford, CA (US);
Inventors:
Dongcheng Dai, Mountain View, CA (US);
John H. Musser, San Carlos, CA (US);
Edwin S. Lennox, Stanford, CA (US);
Assignee:
Pharmagenesis, Inc., Palo Alto, CA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 307/77 (2006.01);
U.S. Cl.
CPC ...
Abstract
Variously substituted carbonate and carbamate derivatives of triptolide compounds have good aqueous solubility and convert to biologically active compounds in vivo, at a rate which can be modulated by varying the substitution on the prodrug. The prodrugs are useful as immunosuppressive, anti-inflammatory and anticancer agents.