The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 07, 2010

Filed:

Jun. 08, 2007
Applicants:

Ashok Kumar, Maharashtra, IN;

Dharmendra Singh, Maharashtra, IN;

Swapnali Hemant Patil, Maharashtra, IN;

Ganesh Devidas Mahale, Maharashtra, IN;

Uttamrao Arjunrao Sawant, Maharashtra, IN;

Balasaheb Ganpat Jadhav, Maharashtra, IN;

Ragneshkumar Rana, Maharashtra, IN;

Inventors:

Ashok Kumar, Maharashtra, IN;

Dharmendra Singh, Maharashtra, IN;

Swapnali Hemant Patil, Maharashtra, IN;

Ganesh Devidas Mahale, Maharashtra, IN;

Uttamrao Arjunrao Sawant, Maharashtra, IN;

Balasaheb Ganpat Jadhav, Maharashtra, IN;

Ragneshkumar Rana, Maharashtra, IN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 281/16 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed herein is an industrial preparation of Quetiapine by the reaction of 11-piperazinyldibenzo[b,f][1,4]-thiazepine or its salt with 2-(2-chloroethoxy)ethanol in presence of an organic or inorganic base under neat or aqueous condition to form 11-[4-{2-(2-hydroxyethoxy)ethyl}-1-piperazinyl]dibenzo[b,f]-[1,4]thiazepine. The quetiapine free base obtained is further converted to its hemi-fumarate salt.


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