The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 07, 2010

Filed:

Jun. 12, 2007
Applicants:

Ingo Hartung, Berlin, DE;

Stuart Ince, Berlin, DE;

Georg Kettschau, Berlin, DE;

Karl-heinz Thierauch, Berlin, DE;

Hans Briem, Bremen, DE;

Ulf Boemer, Glienicke/Nordbahn, DE;

Inventors:

Ingo Hartung, Berlin, DE;

Stuart Ince, Berlin, DE;

Georg Kettschau, Berlin, DE;

Karl-Heinz Thierauch, Berlin, DE;

Hans Briem, Bremen, DE;

Ulf Boemer, Glienicke/Nordbahn, DE;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/44 (2006.01); A61K 31/501 (2006.01); A61K 31/535 (2006.01); A61P 43/00 (2006.01); C07D 401/00 (2006.01); C07D 413/00 (2006.01); C07D 471/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to substituted pyrazolopyridines according to the general formula (I): in which A, B, D, E, R, R, R, R, R, Rand q are as defined in the claims, and salts thereof, to pharmaceutical compositions comprising said substituted pyrazolopyridine compounds, to methods of preparing said substituted pyrazolopyridines, as well as to uses thereof for manufacturing a pharmaceutical composition for the treatment of diseases of dysregulated vascular growth or of diseases which are accompanied with dysregulated vascular growth, wherein the compounds effectively interfere with Tie2 signalling.


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