The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 07, 2010
Filed:
Aug. 16, 2004
Jene A. Golovchenko, Lexington, MA (US);
Jiali LI, Fayetteville, AR (US);
Derek Stein, Delft, NL;
Marc H. Gershow, Cambridge, MA (US);
Jene A. Golovchenko, Lexington, MA (US);
Jiali Li, Fayetteville, AR (US);
Derek Stein, Delft, NL;
Marc H. Gershow, Cambridge, MA (US);
President and Fellows of Harvard College, Cambridge, MA (US);
Abstract
The invention features methods for evaluating the conformation of a polymer, for example, for determining the conformational distribution of a plurality of polymers and to detect binding or denaturation events. The methods employ a nanopore which the polymer, e.g., a nucleic acid, traverses. As the polymer traverses the nanopore, measurements of transport properties of the nanopore yield data on the conformation of the polymer.