The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 07, 2010

Filed:

Jul. 24, 2006
Applicants:

Jean-christophe Renauld, Brussels, BE;

Diane Lejeune, Brussels, BE;

Laure Dumoutier, Brussels, BE;

Inventors:

Jean-Christophe Renauld, Brussels, BE;

Diane Lejeune, Brussels, BE;

Laure Dumoutier, Brussels, BE;

Assignee:

Wyeth, Madison, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/00 (2006.01); G01N 33/48 (2006.01); G01N 33/50 (2006.01); G01N 33/53 (2006.01); G01N 33/68 (2006.01); C07K 14/54 (2006.01); C07K 14/705 (2006.01); C07K 14/715 (2006.01);
U.S. Cl.
CPC ...
Abstract

Interleukin-22 interacts with its receptor, referred to as IL-22R, and instigates a series of reactions, leading to activation of various molecules, such as JAK-1, Tyk2, and others. One can identify molecules which mediate this interaction by measuring the activity of one or more of the molecules in the pathway, to identify agonists and antagonists. These, in turn, are useful therapeutic agents, where inappropriate expression of one of the activated molecules is at issue, and requires amelioration.


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