The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 07, 2010
Filed:
Feb. 12, 2008
Applicants:
S. Ananth Karumanchi, Chestnut Hill, MA (US);
Sharon Maynard, Newton, MA (US);
Vikas P. Sukhatme, Newton, MA (US);
Inventors:
S. Ananth Karumanchi, Chestnut Hill, MA (US);
Sharon Maynard, Newton, MA (US);
Vikas P. Sukhatme, Newton, MA (US);
Assignee:
Beth Israel Deaconess Medical Center, Boston, MA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 39/00 (2006.01); G01N 33/53 (2006.01); C07K 17/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
Disclosed herein are methods for diagnosing pre-eclampsia and eclampsia. Also disclosed herein are methods for treating pre-eclampsia and eclampsia using compounds that increase VEGF or PlGF levels or compounds that decrease sFlt-1 levels. Compounds that inhibit the binding of VEGF or PlGF to sFlt1—are also disclosed herein for the treatment of pre-eclampsia or eclampsia.