The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 07, 2010
Filed:
Oct. 14, 2005
Michael Chorny, Philadelphia, PA (US);
Boris Polyak, Philadelphia, PA (US);
Ilia Fishbein, Philadelphia, PA (US);
Ivan Alferiev, Clementon, NJ (US);
Robert J. Levy, Merion Station, PA (US);
Michael Chorny, Philadelphia, PA (US);
Boris Polyak, Philadelphia, PA (US);
Ilia Fishbein, Philadelphia, PA (US);
Ivan Alferiev, Clementon, NJ (US);
Robert J. Levy, Merion Station, PA (US);
The Children's Hospital of Philadelphia, Philadelphia, PA (US);
Abstract
A particle including a matrix-forming agent and a polyelectrolyte-amphiphilic agent adduct wherein the polyelectrolyte-amphiphilic agent adduct is in physical communication with the matrix-forming agent. The particle further includes a coated magnetic field-responsive agent and a biomaterial. Methods of making the particle are provided. Also provided are methods of delivery of the biomaterial to a target cell or a target tissue including administering the particle having the matrix-forming agent, polyelectrolyte-amphiphilic agent adduct, the coated magnetic field-responsive agent and the biomaterial; providing a magnetic device associated with the target cell or the target tissue; applying a magnetic force to the particle; and guiding the particle toward the magnetic device by the magnetic force.