The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 30, 2010

Filed:

Sep. 16, 2003
Applicants:

Benedikt Sas, Stekene, BE;

Johan Van Hemel, Antwerp, BE;

Jan Vandenkerckhove, Zichem, BE;

Eric Peys, Balen, BE;

Johan Neyts, Kessel Lo, BE;

Inventors:

Benedikt Sas, Stekene, BE;

Johan Van hemel, Antwerp, BE;

Jan Vandenkerckhove, Zichem, BE;

Eric Peys, Balen, BE;

Johan Neyts, Kessel Lo, BE;

Assignee:

Kemin Foods, L.C., Des Moines, IA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/335 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The use of sesquiterpenes and, in particular sesquiterpene lactone endoperoxides, such as artemisinin and analogs thereof, for the treatment of hepatitis C virus infections. Artemisinin, analogs of artemsisnin and some crudeextracts were tested in vitro against DNA-viruses, retro-viruses and, (an important family of human and animal RNA pathogens). These compounds were also screened for anti-tumor activity. Strong activity of artemisinin was noticed against the bovine viral diarrhea virus (BVDV). As pestiviruses, such as BVDV, share many similarities with hepatitis C virus (HCV), we can conclude that endoperoxides in general and artemisinin more specifically have efficacy as treatments for hepatitis C viral infections.


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