The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 30, 2010
Filed:
Nov. 19, 2002
Robin Hwang, Cary, NC (US);
Vincent Sullivan, Cary, NC (US);
Juan Huang, Cary, NC (US);
Zhaolin Wang, Edmonton, CA;
John A. Mikszta, Durham, NC (US);
David Montgomery, Cary, NC (US);
Brandi Ford, Apex, NC (US);
Anjana Bhuta-wills, Cary, NC (US);
Robin Hwang, Cary, NC (US);
Vincent Sullivan, Cary, NC (US);
Juan Huang, Cary, NC (US);
Zhaolin Wang, Edmonton, CA;
John A. Mikszta, Durham, NC (US);
David Montgomery, Cary, NC (US);
Brandi Ford, Apex, NC (US);
Anjana Bhuta-Wills, Cary, NC (US);
Becton, Dickinson and Company, Franklin Lakes, NJ (US);
Abstract
A method of preparing a pharmaceutical composition is described, comprising 1) atomizing a liquid formulation of a therapeutic agent to produce an atomized formulation; 2) freezing said atomized formulation to form solid particles; and 3) drying said solid particles at about atmospheric pressure to produce a powder, wherein said drying is performed in the presence of vibration, internals, mechanical stirring, or a combination thereof. Another method is described, comprising 1) atomizing a liquid formulation of a therapeutic agent to produce an atomized formulation; 2) freezing said atomized formulation to form solid particles; and 3) drying said solid particles to produce a powder; wherein the atomized formulation comprises droplets having an average mean diameter of between about 35μ and about 300μ, and/or the powder comprises dried particles having an average mean diameter of between about 35μ and about 300μ. Compositions made by the above methods, and methods of using the compositions, are also described.