The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 23, 2010
Filed:
Apr. 30, 2004
Ali AL Mourabit, Gif-suf-Yvette, FR;
Nathalie Travert, Gif-sur-Yvette, FR;
Robert Abou-jneid, Paris, FR;
Saïd Ghoulami, Orsay, FR;
Ali Al Mourabit, Gif-suf-Yvette, FR;
Nathalie Travert, Gif-sur-Yvette, FR;
Robert Abou-Jneid, Paris, FR;
Saïd Ghoulami, Orsay, FR;
Centre National de la Recherche Scientifique (C.N.R.S.), Paris, FR;
Universite de Paris Sud, Orsay, FR;
Abstract
The invention relates to a method of synthesizing heterocyclic compounds. The invention is characterised in that it consists in opening a compound having formula (I), wherein: —X represents NH, O, S or a N-p group, p being a protective group, such as Boc or Troc; —Y represents N, O, S; —Z represents NHor NH-p; and —Rrepresents a C-Calkoxy radical, aryloxy, such as phenyloxy, or a pyrrolyl radical, said radicals being optionally substituted, or the salts thereof, and the isomers of the aforementioned compounds. Moreover, the above-mentioned opening step is performed in conditions such as to produce a heterocycle having formula (II), wherein: —X, Y and Z are as defined above; —Rrepresents a —CH═CH—CH—NH—CORor —CH═CH—CH—NH—CO group; and Roccupies one, two or three positions and represents a halogen. The invention can be used to synthesise natural products.