The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 23, 2010

Filed:

May. 30, 2008
Applicants:

Jurg Tschopp, Epalinges, CH;

Catherine Hession, Hingham, MA (US);

Inventors:

Jurg Tschopp, Epalinges, CH;

Catherine Hession, Hingham, MA (US);

Assignees:

Biogen Idec MA Inc., Cambridge, MA (US);

Apoxis S.A., Epalinges, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/08 (2006.01); C07K 16/00 (2006.01); A61K 39/395 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Embodiments of the present invention encompass novel receptors of the TNF family. In particular, embodiments of the invention encompass TNF Receptor in the BRAIN (TRAIN) and isolated antibodies that bind to the same. In some embodiments, isolated antibodies that bind to TRAIN are useful in regulating cell differentiation, death, and survival. Other embodiments of the invention encompass pharmaceutical compositions comprising antibodies that bind to human TRAIN.


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