The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 23, 2010
Filed:
Jun. 04, 2007
Applicants:
Leslie S. Johnson, Darnestown, MD (US);
Ling Huang, Bethesda, MD (US);
Hua LI, North Potomac, MD (US);
Nadine Tuaillon, Sykesville, MD (US);
Inventors:
Leslie S. Johnson, Darnestown, MD (US);
Ling Huang, Bethesda, MD (US);
Hua Li, North Potomac, MD (US);
Nadine Tuaillon, Sykesville, MD (US);
Assignee:
MacroGenics, Inc., Rockville, MD (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C12P 21/08 (2006.01); C07K 14/00 (2006.01); C12N 15/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
CD16A binding proteins useful for the reduction of a deleterious immune response are described. In one aspect, humanized anti-cd16A antibodies, optionally lacking effector function, are used for the treatment of immune disorders such as idiopathic thrombocytopenic purpura and autoimmune hemolytic anemia.