The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 23, 2010
Filed:
Jun. 14, 2005
Susan M. Smith, Madison, WI (US);
John W. Lough, Elm Grove, WI (US);
George R. Flentke, Madison, WI (US);
Susan M. Smith, Madison, WI (US);
John W. Lough, Elm Grove, WI (US);
George R. Flentke, Madison, WI (US);
Wisconsin Alumni Research Foundation, Madison, WI (US);
MCW Research Foundation, Inc., Milwaukee, WI (US);
Abstract
A method for treating or preventing cardiac hypertrophy in a mammal, comprising manipulating levels of RBP, retinoids, or an affiliated signaling and regulatory pathway in the mammal. Preferably, the method comprises reducing or inhibiting the level of RBP or retinoids or their signaling pathway, or an affiliated signaling pathway, via a dietary, genetic, protein-based, or pharmacologic approach, or a combination thereof. Also disclosed are pharmaceutical composition suitable for the method.